Herv´e Lebrec: search on Z-Library

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1

Assessment of Apoptosis in Xenobiotic-Induced Immunotoxicity

Marc Pallardy, Armelle Biola, Hervé Lebrec, Jacqueline Bréard

Journal:

Year:

1999

Language:

english

File:

PDF, 213 KB

english, 1999

2

Summary of a workshop on nonclinical and clinical immunotoxicity assessment of immunomodulatory drugs

Piccotti, Joseph R., Lebrec, Herve N., Evans, Ellen, Herzyk, Danuta J., Hastings, Kenneth L., Burns-Naas, Leigh Ann, Gourley, Ian S., Wierda, Daniel, Kawabata, Thomas T.

Journal:

Journal of Immunotoxicology

Year:

2009

Language:

english

File:

PDF, 597 KB

english, 2009

3

A summary of meeting proceedings for ‘Measuring immune responses in non-human primates for drug development—Opportunities and challenges for predicting human efficacy and immunotoxicity’

Kamperschroer, Cris, Kaur, Amitinder, Lebrec, Hervé

Journal:

Journal of Immunotoxicology

Year:

2012

Language:

english

File:

PDF, 849 KB

english, 2012

4

Diagnosis of portopulmonary hypertension in candidates for liver transplantation: A prospective study

Isabelle O. Colle, Richard Moreau, Erica Godinho, Jacques Belghiti, Florence Ettori, Alain Cohen-Solal, Hervé Mal, Jacques Bernuau, Jean Marty, Didier Lebrec, Dominique Valla, François Durand

Journal:

Year:

2003

Language:

english

File:

PDF, 140 KB

english, 2003

5

Current Concepts in Natural Killer Cell Biology and Application to Drug Safety Assessments

Goyos, Ana, Fort, Madeline, Sharma, Amy, Lebrec, Herve

Journal:

Toxicological Sciences

Year:

2019

Language:

english

File:

PDF, 774 KB

english, 2019

6

Overview of the nonclinical quality and toxicology testing for recombinant biopharmaceuticals produced in mammalian cells

Hervé Lebrec, Padma Narayanan, Raymond Nims

Journal:

Journal of Applied Toxicology

Year:

2011

File:

PDF, 29 KB

2011

7

847 The Fully Human Anti-IL-15 Antibody AMG 714, in Development for Celiac and Refractory Celiac Disease, Does Not Reduce Circulating Numbers of Human Natural Killer Cells or Preclude Their In Vitro Activation and Function

Gorski, Kevin, Butz, Eric, Leon, Francisco, Lebrec, Herve, Tsuji, Wayne H.

Journal:

Gastroenterology

Year:

2016

Language:

english

File:

PDF, 200 KB

english, 2016

8

Effect of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) on Pulmonary Influenza Virus Titer and Natural Killer (NK) Activity in Rats

Yung G. Yang, Hervé Lebrec, Gary R. Burleson

Journal:

Fundamental and Applied Toxicology

Year:

1994

File:

PDF, 413 KB

1994

9

Prevention of hepatopulmonary syndrome and hyperdynamic state by pentoxifylline in cirrhotic rats

Sztrymf, B., Rabiller, A., Nunes, H., Savale, L., Lebrec, D., Le Pape, A., de Montpreville, V., Mazmanian, M., Humbert, M., Herve, P.

Journal:

European Respiratory Journal

Year:

2004

Language:

english

File:

PDF, 393 KB

english, 2004

10

Quantitation of Cytokine mRNA Expression as an Endpoint for Prediction and Diagnosis of Xenobiotic-Induced Hypersensitivity Reactions

Isabelle Gaspard, Saadia Kerdine, Marc Pallardy, Hervé Lebrec

Journal:

Year:

1999

Language:

english

File:

PDF, 193 KB

english, 1999

11

Pulmonary vascular disorders in portal hypertension

Hervé, P., Lebrec, D., Brenot, F., Simonneau, G., Humbert, M., Sitbon, O., Duroux, P.

Journal:

European Respiratory Journal

Year:

1998

Language:

english

File:

PDF, 303 KB

english, 1998

12

An inter-laboratory retrospective analysis of immunotoxicological endpoints in non-human primates: Flow cytometry immunophenotyping

Krejsa, Cecile M., Neradilek, Moni Blazej, Polissar, Nayak L., Cox, Nick, Clark, Darcey, Cowan, Laine, Bussiere, Jeanine, Lebrec, Herve

Journal:

Journal of Immunotoxicology

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

13

Effect of 2,3,7,8-Tetrachlorodibenzo- p -dioxin (TCDD) on Influenza Virus Host Resistance in Mice

BURLESON, GARY R., LEBREC, HERVÈ, YANG, YUNG G., IBANES, JOELLE D., PENNINGTON, KEVIN N., BIRNBAUM, LINDA S.

Journal:

Toxicological Sciences

Year:

1996

Language:

english

File:

PDF, 1.85 MB

english, 1996

14

Prevention of Gram-Negative Translocation Reduces the Severity of Hepatopulmonary Syndrome

Rabiller, Anne, Nunes, Hilario, Lebrec, Didier, Tazi, Khalid A., Wartski, Myriam, Dulmet, Elisabeth, Libert, Jean-Marie, Mougeot, Christine, Moreau, Richard, Mazmanian, Michel, Humbert, Marc, Hervé, P

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2002

Language:

english

File:

PDF, 75 KB

english, 2002

15

Norfloxacin Reduces Aortic NO Synthases and Proinflammatory Cytokine Up-Regulation in Cirrhotic Rats: Role of Akt Signaling

Khalid A. Tazi, Richard Moreau, Philippe Hervé, Agnes Dauvergne, Dominique Cazals-Hatem, Frederic Bert, Odile Poirel, Anne Rabiller, Didier Lebrec

Journal:

Gastroenterology

Year:

2005

Language:

english

File:

PDF, 742 KB

english, 2005

16

Cirrhotic rats with bacterial translocation have higher incidence and severity of hepatopulmonary syndrome

BENJAMIN SZTRYMF, JEAN-MARIE LIBERT, CHRISTINE MOUGEOT, DIDIER LEBREC, MICHEL MAZMANIAN, MARC HUMBERT, PHILIPPE HERVE

Journal:

Journal of Gastroenterology and Hepatology

Year:

2005

Language:

english

File:

PDF, 190 KB

english, 2005

17

Survey: Immune function and immunotoxicity assessment in dogs

Lebrec, Hervé, O’Lone, Raegan, Freebern, Wendy, Komocsar, Wendy, Moore, Peter

Journal:

Journal of Immunotoxicology

Year:

2012

Language:

english

File:

PDF, 720 KB

english, 2012

18

Portopulmonary Hypertension

Le Pavec, Jérôme, Souza, Rogério, Herve, Philippe, Lebrec, Didier, Savale, Laurent, Tcherakian, Colas, Jaïs, Xavier, Yaïci, Azzedine, Humbert, Marc, Simonneau, Gérald, Sitbon, Olivier

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2008

Language:

english

File:

PDF, 114 KB

english, 2008

19

An inter-laboratory retrospective analysis of immunotoxicological endpoints in non-human primates: T-cell-dependent antibody responses

Lebrec, Hervé, Cowan, Laine, Lagrou, Michelle, Krejsa, Cecile, Neradilek, Moni B., Polissar, Nayak L., Black, Lauren, Bussiere, Jeanine

Journal:

Journal of Immunotoxicology

Year:

2011

Language:

english

File:

PDF, 1.40 MB

english, 2011

20

Interleukin-10 and interleukin-4 have similar effects on hapten-specific primary antibody responses to penicillin in vivo

Saadia Kerdine, Marc Pallardy, Sandrine Lamanètre, Jacques Bertoglio, Hervé Lebrec

Journal:

European Journal of Immunology

Year:

1996

Language:

english

File:

PDF, 485 KB

english, 1996

21

Immunotoxicological Investigation Using Pharmaceutical Drugs: In Vivo Evaluation of Immune Effects

Herve Lebrec, Christian Blot, Sophie Pequet, Remi Roger, Claude Bohuon, Marc Pallardy

Journal:

Fundamental and Applied Toxicology

Year:

1994

File:

PDF, 571 KB

1994

22

Evidence for an Association Between Intrahepatic Vascular Changes and the Development of Hepatopulmonary Syndrome

Lejealle, Clément, Paradis, Valérie, Bruno, Onorina, de Raucourt, Emmanuelle, Francoz, Claire, Soubrane, Olivier, Lebrec, Didier, Bedossa, Pierre, Valla, Dominique, Mal, Hervé, Vilgrain, Valérie, Dura

Journal:

Year:

2018

Language:

english

File:

PDF, 3.32 MB

english, 2018

23

EFFECT OF INFLUENZA VIRUS INFECTION ON OVALBUMIN SPECIFIC IgE RESPONSES TO INHALED ANTIGEN IN THE RAT

Herv Lebrec Katherine Sarlo Gary R,

Journal:

Journal of Toxicology and Environmental Health

Year:

1996

Language:

english

File:

PDF, 347 KB

english, 1996

24

Th1/Th2 responses to drugs

Hervé Lebrec, Saadia Kerdine, Isabelle Gaspard, Marc Pallardy

Journal:

Year:

2001

Language:

english

File:

PDF, 68 KB

english, 2001

25

Overview of the nonclinical quality and toxicology testing for recombinant biopharmaceuticals produced in mammalian cells

Hervé Lebrec, Padma Narayanan, Raymond Nims

Journal:

Journal of Applied Toxicology

Year:

2010

Language:

english

File:

PDF, 553 KB

english, 2010

26

Tumor necrosis factor, tumor necrosis factor inhibition, and cancer risk

Lebrec, Hervé, Ponce, Rafael, Preston, Bradley D., Iles, Jan, Born, Teresa L., Hooper, Michele

Journal:

Current Medical Research and Opinion

Year:

2015

Language:

english

File:

PDF, 2.68 MB

english, 2015

27

Influenza virus host resistance models in mice and rats: utilization for immune function assessment and immunotoxicology

Hervé Lebrec, Gary R. Burleson

Journal:

Year:

1994

Language:

english

File:

PDF, 571 KB

english, 1994

28

Immunotoxicological Investigation Using Pharmaceutical Drugs: In Vivo Evaluation of Immune Effects

LEBREC, HERVE, BLOT, CHRISTIAN, PEQUET, SOPHIE, ROGER, REMI, BOHUON, CLAUDE, PALLARDY, MARC

Journal:

Toxicological Sciences

Year:

1994

Language:

english

File:

PDF, 919 KB

english, 1994

29

Role of Nitric Oxide in Hepatopulmonary Syndrome in Cirrhotic Rats

NUNES, HILARIO, LEBREC, DIDIER, MAZMANIAN, MICHEL, CAPRON, FRÉDÉRIQUE, HELLER, JÖRG, TAZI, KHALID A., ZERBIB, ERIC, DULMET, ELISABETH, MOREAU, RICHARD, DINH-XUAN, A. TUAN, SIMONNEAU, GERALD, HERVÉ, PH

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2001

Language:

english

File:

PDF, 177 KB

english, 2001

30

Immunophenotyping: Application to Safety Assessment

Wang, Xiaoting, Lebrec, Hervé

Journal:

Toxicologic Pathology

Year:

2017

Language:

english

File:

PDF, 410 KB

english, 2017

31

Cirrhosis ameliorates monocrotaline-induced pulmonary hypertension in rats

Le Pavec, J., Perros, F., Eddahibi, S., Decante, B., Dorfmuller, P., Sitbon, O., Lebrec, D., Humbert, M., Mazmanian, M., Herve, P.

Journal:

European Respiratory Journal

Year:

2009

Language:

english

File:

PDF, 699 KB

english, 2009

32

IL-4 and IFN-γ mRNA Induction in Human Peripheral Lymphocytes Specific for β-Lactam Antibiotics in Immediate or Delayed Hypersensitivity Reactions

Isabelle Gaspard, Marie-Th´er`ese Guinnepain, J´erome Laurent, Nicolas Bachot, Saadia Kerdine, Jacques Bertoglio, Marc Pallardy, Herv´e Lebrec

Journal:

Journal of Clinical Immunology

Year:

2000

Language:

english

File:

PDF, 1.38 MB

english, 2000

33

Effect of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) on Influenza Virus Host Resistance in Mice

Gary R. Burleson, Hervé Lebrec, Yung G. Yang, Joelle D. Ibanes, Kevin N. Pennington, Linda S. Birnbaum

Journal:

Fundamental and Applied Toxicology

Year:

1996

Language:

english

File:

PDF, 123 KB

english, 1996

34

Deleterious Effects of β-Blockers on Exercise Capacity and Hemodynamics in Patients With Portopulmonary Hypertension

Steeve Provencher, Philippe Herve, Xavier Jais, Didier Lebrec, Marc Humbert, Gerald Simonneau, Olivier Sitbon

Journal:

Gastroenterology

Year:

2006

Language:

english

File:

PDF, 116 KB

english, 2006

35

The T-cell-dependent antibody response assay in nonclinical studies of pharmaceuticals and chemicals: Study design, data analysis, interpretation

Lebrec, Hervé, Molinier, Brigitte, Boverhof, Darrell, Collinge, Mark, Freebern, Wendy, Henson, Kristin, Mytych, Daniel T., Ochs, Hans D., Wange, Ronald, Yang, Yung, Zhou, Lei, Arrington, Joshua, Chris

Journal:

Regulatory Toxicology and Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.50 MB

english, 2014

36

Modernizing Human Cancer Risk Assessment of Therapeutics

Fielden, Mark R., Ward, Lucas D., Minocherhomji, Sheroy, Nioi, Paul, Lebrec, Herve, Jacobson-Kram, David

Journal:

Trends in Pharmacological Sciences

Year:

2017

Language:

english

File:

PDF, 2.34 MB

english, 2017

37

Prevention of hepatopulmonary syndrome by pentoxifylline in rats with cirrhosis

B. Sztrymf, A. Rabiller, R. Moreau, O. Poirel, M. Mazmanian, A. Le Pape, D. Lebrec, P. Herve

Journal:

Journal of Hepatology

Year:

2003

Language:

english

File:

PDF, 161 KB

english, 2003

38

Immunomodulation and lymphoma in humans

Ponce, Rafael A., Gelzleichter, Thomas, Haggerty, Helen G., Heidel, Shawn, Holdren, Matthew S., Lebrec, Herve, Mellon, R. Daniel, Pallardy, Marc

Journal:

Journal of Immunotoxicology

Year:

2014

Language:

english

File:

PDF, 510 KB

english, 2014

39

Immune modification due to chemical interference with transmembrane signalling: Application to polycyclic aromatic hydrocarbons

Marc Pallardy, Zohair Mishal, Hervé Lebrec, Claude Bohuon

Journal:

International Journal of Immunopharmacology

Year:

1992

Language:

english

File:

PDF, 425 KB

english, 1992

40

Development of a BiTE ® -mediated CD8 + cytotoxic T-lymphocyte activity assay to assess immunomodulatory potential of drug candidates in Cynomolgus macaque

Frank, Brendon, Wei, Yu-Ling, Kim, Kyung-Hoon, Guerrero, Abraham, Lebrec, Hervé, Balazs, Mercedesz, Wang, Xiaoting

Journal:

Journal of Immunotoxicology

Year:

2018

Language:

english

File:

PDF, 1.27 MB

english, 2018

41

Evaluation of a Lymph Node Proliferation Assay for its Ability to Detect Pharmaceuticals with Potential to Cause Immune-Mediated Drug Reactions

Weaver, James L., Chapdelaine, Joan M., Descotes, Jacques, Germolec, Dori, Holsapple, Mike, House, Robert, Lebrec, Herve, Meade, Jean, Pieters, Raymond, Hastings, Kenneth L., Dean, Jack H.

Journal:

Journal of Immunotoxicology

Year:

2005

Language:

english

File:

PDF, 128 KB

english, 2005

42

Immunotoxicological investigation using pharmaceutical drugs. In vitro evaluation of immune effects using rodent or human immune cells

Hervé Lebrec, Rémi Roger, Christian Blot, Gary R. Burleson, Claude Bohuon, Marc Pallardy

Journal:

Year:

1995

Language:

english

File:

PDF, 1005 KB

english, 1995

43

Effect of 2,3,7,8-Tetrachlorodibenzo- p -dioxin (TCDD) on Pulmonary Influenza Virus Titer and Natural Killer (NK) Activity in Rats

YANG, YUNG G., LEBREC, HERVÉ, BURLESON, GARY R.

Journal:

Toxicological Sciences

Year:

1994

Language:

english

File:

PDF, 666 KB

english, 1994

44

Modeling the pharmacokinetic-pharmacodynamic relationship of the monoclonal anti-macaque-IL-15 antibody Hu714MuXHu in cynomolgus monkeys

Pan, Wei. J., Li, Hong, Xiao, Jim J., Horner, Michelle J., Lebrec, Herve N., Butz, Eric A., Kaliyaperumal, Arunan, Cheah, Tsui C., Ortiz, Robert C., Prokop, Samantha P., Buntich, Sabina A., Boren, Bab

Journal:

Pharmacology Research & Perspectives

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

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